AlphaPeptide Technical Profile

TB-500 Fragment 17-23 Technical Profile: Ac-LKKTETQ Sequence, Molecular Identity and Research Background

A technical overview of TB-500 Fragment 17-23, covering its Ac-LKKTETQ sequence, thymosin beta-4 fragment identity, CAS number, molecular formula, molecular weight, research background, analytical verification, storage considerations, and product documentation review points.

Core Summary

TB-500 Fragment 17-23 is a synthetic thymosin beta-4-derived peptide fragment used for laboratory research and technical product evaluation. Unlike full-length thymosin beta-4, which contains 43 amino acids, TB-500 Fragment 17-23 refers to a much shorter N-terminally acetylated heptapeptide sequence commonly written as Ac-LKKTETQ.

This distinction is important for product identity review. TB-500 Fragment 17-23 should not be confused with full-length thymosin beta-4, because the two materials differ significantly in peptide length, molecular weight, structural scope, and analytical verification requirements.

Product Identity Overview

Product Name: TB-500 Fragment 17-23
Common Sequence: Ac-LKKTETQ
Full Sequence Name: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
CAS No.: 885340-08-9
Molecular Formula: C38H68N10O14
Molecular Weight: 889.00 g/mol
Peptide Length: 7 amino acids
Parent Reference Peptide: Thymosin beta-4
Structural Type: N-terminally acetylated synthetic peptide fragment
Common Format: Lyophilized peptide powder
Product Page: View TB-500 Fragment 17-23 product specifications and available vial options

Molecular Identity and Structural Context

TB-500 Fragment 17-23 corresponds to residues 17-23 of thymosin beta-4, a naturally occurring 43-amino-acid peptide involved in actin-related biochemical research. The fragment sequence is generally represented as Ac-LKKTETQ, where the N-terminal acetyl group is part of the defined molecular identity.

From an analytical perspective, the acetylated seven-residue structure is central to confirming the correct material. A molecular weight near 889 g/mol is consistent with the acetylated fragment, while full-length thymosin beta-4 has a much larger molecular mass. For this reason, customers reviewing TB-500 Fragment 17-23 should confirm that the product documentation, COA, HPLC data, and specification sheet describe the fragment rather than the full-length parent peptide.

Research Background

The research history of TB-500 Fragment 17-23 is closely linked to thymosin beta-4 and its actin-binding region. Scientific interest in thymosin beta-4 has focused on its structural relationship with actin regulation, cell-migration models, and related biochemical pathways. Later analytical work identified the short N-terminally acetylated 17-23 fragment, Ac-LKKTETQ, as a distinct synthetic peptide material requiring its own identity verification.

This makes TB-500 Fragment 17-23 especially important in technical research settings where exact sequence identity matters. Rather than treating “TB-500” as a generic label, researchers and purchasing teams should confirm whether the material is the acetylated heptapeptide fragment or a different thymosin beta-4-related peptide.

Technical Specification Review

A technical review of TB-500 Fragment 17-23 should begin with product identity confirmation. The CAS number, molecular formula, molecular weight, sequence, and product format should be checked against the product page and available batch-level documentation.

Important review points include:

Whether the listed sequence is Ac-LKKTETQ
Whether the CAS number is listed as 885340-08-9
Whether the molecular formula is shown as C38H68N10O14
Whether the molecular weight is approximately 889.00 g/mol
Whether the COA and HPLC report refer to the same batch number
Whether purity, peptide content, water content, and impurity data are clearly documented
Whether the storage and handling notes match the supplied product format

These parameters help customers confirm that the product identity, analytical documentation, and specification data are aligned.

Analytical Verification

TB-500 Fragment 17-23 is commonly reviewed using HPLC and mass-based identity confirmation. HPLC documentation supports chromatographic purity review, while mass-related analytical data can help confirm whether the detected material corresponds to the expected acetylated heptapeptide.

For quality review, customers should compare the product page with the available COA, HPLC report, and specification sheet. The most useful documentation usually includes product name, batch number, sequence or identity reference, purity, peptide content, water content, single impurity data, and analytical method.

Storage and Packaging Considerations

TB-500 Fragment 17-23 is typically supplied as a lyophilized peptide powder in sealed vial packaging. Storage requirements may vary by product format, batch, and shipping destination, so customers should always follow the storage information shown in the applicable product documentation.

For product review, storage information should be checked together with packaging format, batch number, and available quality files. This helps ensure that the material being reviewed matches the documentation provided for that specific product lot.

Compliance and Intended Use

TB-500 Fragment 17-23 products are supplied for research and laboratory use only. The information in this article is provided for technical product review, molecular identity confirmation, and documentation evaluation.

This article does not provide dosage, administration, therapeutic, diagnostic, veterinary, clinical, or patient-use guidance. Customers are responsible for confirming applicable local rules, import requirements, institutional policies, and handling requirements before ordering or using any research material.