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BPC-157 Technical Profile: Peptide Identity, Research History, and Molecular Characterization

A technical profile of BPC-157 covering its peptide identity, CAS number, amino acid sequence, molecular formula, molecular weight, historical research background, analytical characterization, storage considerations, and research-use compliance boundaries.

BPC-157 Technical Profile: Peptide Identity, Research History, and Molecular Characterization

Core Summary

BPC-157 is a synthetic pentadecapeptide, meaning it is composed of 15 amino acids. It is commonly referenced in laboratory research as a defined synthetic peptide sequence associated with early gastric peptide research and later preclinical studies involving peptide stability, biological signaling, and tissue-response models.

From a technical product review perspective, BPC-157 should be evaluated through its peptide sequence, molecular formula, molecular weight, CAS number, analytical characterization, batch identity, and storage documentation. These data points help researchers and purchasing teams confirm that the listed material matches the expected peptide identity before laboratory evaluation.

Core Peptide Identity

BPC-157 is a short synthetic peptide with a defined 15-amino-acid sequence. Compared with larger modified peptides, its technical identity is relatively direct: the sequence, molecular formula, and molecular weight are central to product verification.

Key identity parameters include:

  • Product Name: BPC-157
  • Full Name: Body Protection Compound 157
  • CAS Number: 137525-51-0
  • Molecular Formula: C62H98N16O22
  • Molecular Weight: 1419.5 g/mol
  • Peptide Length: 15 amino acids
  • Amino Acid Sequence:: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH
  • Product Type: Synthetic pentadecapeptide
  • Physical Form: Commonly supplied as lyophilized peptide powder

Research History and Development Background

The research history of BPC-157 is closely connected to gastric peptide research in the early 1990s. The abbreviation “BPC” refers to “Body Protection Compound,” a naming convention used in research around peptide fractions associated with gastric juice-derived proteins. BPC-157 refers to the specific 15-amino-acid sequence that became the most widely discussed synthetic fragment in this research area.

Early work focused on identifying peptide fragments that remained stable under challenging biological conditions. BPC-157 drew attention because the sequence was reported in research literature as unusually stable for a peptide of its size, especially in relation to gastric-environment models.

Over the following decades, BPC-157 appeared in a broad preclinical research record. Published studies and later reviews have discussed the peptide in relation to experimental models involving gastrointestinal integrity, vascular response, tendon and ligament models, muscle and bone models, and signaling-pathway research. These studies are best understood as preclinical research literature, not as proof of approved clinical use.

More recent reviews have emphasized the gap between the size of the preclinical literature and the limited state of validated human clinical development. For product documentation, this means BPC-157 should be described carefully as a research-use peptide with a defined sequence and technical identity, rather than as an approved therapeutic material.

Molecular and Structural Characteristics

BPC-157 is a linear peptide consisting of glycine, glutamic acid, proline, lysine, alanine, aspartic acid, leucine, and valine residues. The sequence includes multiple proline residues near the N-terminal region, which is a notable structural feature when reviewing the peptide’s identity.

The sequence is: GEPPPGKPADDAGLV

This sequence corresponds to the following amino acid order:Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Va

Because BPC-157 is defined by a short and specific sequence, sequence confirmation and molecular mass review are especially important. A mismatch in sequence, terminal structure, or salt form can change how the product should be identified in technical documentation.

Analytical Characterization

For BPC-157, analytical review usually focuses on peptide identity, purity profile, molecular mass confirmation, and batch consistency. These checks help confirm whether the material aligns with the expected BPC-157 reference identity.

Common analytical review points include:

  • Peptide sequence identity
  • Molecular formula consistency
  • Molecular weight consistency
  • HPLC purity profile
  • Major peak retention behavior
  • Impurity profile
  • Water content or moisture-related data
  • Appearance and physical form
  • Batch number consistency
  • Storage condition notes

HPLC is commonly used to evaluate chromatographic purity. Mass spectrometry may be used to support molecular identity and molecular weight confirmation where available. For a short peptide such as BPC-157, these two analytical views are often central to technical review.

Product Specification Review

When reviewing a BPC-157 product listing, the core specification fields should be internally consistent. The product name, CAS number, sequence, molecular formula, molecular weight, physical form, and vial options should all refer to the same peptide identity.

Important specification fields include:

  • CAS Number: 137525-51-0
  • Molecular Formula: C62H98N16O22
  • Molecular Weight: 1419.5 g/mol
  • Sequence: GEPPPGKPADDAGLV
  • Peptide Length: 15 amino acids
  • Product Type: Synthetic peptide
  • Assay Method: HPLC
  • Package Format: 10vial/kits
  • Quality Review: Batch-specific documentation where available

Customers should compare the product page with the applicable batch documentation before ordering.

Storage and Packaging Considerations

BPC-157 is commonly supplied as a lyophilized peptide powder in sealed vial packaging. Storage requirements should be reviewed according to the applicable product documentation and batch-specific information.

For technical review, customers should check:

  • Whether the product is supplied as lyophilized powder
  • Whether the vial label and product page show consistent identity information
  • Whether storage notes are available for the specific batch
  • Whether packaging information matches the ordered vial format
  • Whether shipment and storage conditions are appropriate for the product format

This section is intended for product documentation review only. It does not provide preparation, reconstitution, dosage, administration, or application instructions.

Research-Use Compliance Boundary

BPC-157 products are supplied for research and laboratory use only. They are not intended for diagnostic, clinical, veterinary, personal, or consumer use.

Customers are responsible for confirming that procurement, importation, possession, handling, storage, and laboratory use comply with applicable local rules, institutional requirements, and jurisdiction-specific regulations.

This article is intended to support product identity review and technical documentation evaluation. It does not provide medical advice, dosage guidance, administration instructions, therapeutic claims, or patient-use information.

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